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Anticoagulated chicken blood suitable for use in complement titration, adsorption procedures, testing for agglutinins/HA assays, and the preparation of stroma as particulate reagents.
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Residual host cell DNA refers to fragments of DNA from the host organism that are left behind after a biological process such as the production of a biopharmaceutical product or the cultivation of a cell line. This residual DNA can potentially contaminate the final product and affect its safety and efficacy.In the context of biopharmaceutical production regulatory agencies such as the FDA and EMA have set limits on the amount of residual host cell DNA that is acceptable in a final product. These limits vary depending on the type of product and the route of administration and residue host cell DNA quantitative kits are designed to ensure that the final product is safe for human use.
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Adeno-associated virus (AAV) has become one of the most important gene vectors in the field of gene therapy due to its long-term expression low toxicity low immunogenicity and high tissue specificity.Most successful AAV gene therapies for preclinical and clinical studies are limited to natural serotypes but the presence of neutralizing antibodies against AAV remains a significant barrier to systemic delivery.
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APC-Labeled Human DLL3 Protein His Tag (DL3-HA2H8) is produced via conjugation of APC to Human DLL3 Protein His Tag with a new generation site-specific technology under Star Staining labeling platform. Human DLL3 Protein His Tag is is expressed from human 293 cells (HEK293). It contains AA Ala 27 - Leu 492 (Accession # Q9NYJ7-1).
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PE-Labeled Human CLEC12A Protein His Tag (CLA-HP245) is produced via conjugation of PE to Human CLEC12A Protein His Tag with a new generation site-specific technology under Star Staining labeling platform. Human CLEC12A Protein His Tag is expressed from human 293 cells (HEK293). It contains AA His 65 - Ala 265 (Accession # Q5QGZ9-2).
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Monoclonal Anti-Human-IgG-Fc Antibody Mouse IgG1 is a chimeric monoclonal antibody recombinantly expressed from CHO cells which combines the variable region of a mouse monoclonal antibody with mouse IgG1 constant domain. The mouse monoclonal antibody is produced from a hybridoma resulting from fusion of SP2/0 myeloma and B-lymphocytes obtained from a mouse immunized with IgG Fc.
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Human Epidermal growth factor Receptor 2 (HER2) is also called ERBB2 HER-2HER-2 /neu NEU NGLTKR1 and c-erb B2and is a protein giving higher aggressiveness in breast cancers. It is a member of the ErbB protein family more commonly known as the epidermal growth factor receptor family. HER2 is a cell membrane surface-bound receptor tyrosine kinase and is normally involved in the signal transduction pathways leading to cell growth and differentiation. HER2 is thought to be an orphan receptor with none of the EGF family of ligands able to activate it. Approximately 30% of breast cancers have an amplification of the HER2 gene or overexpression of its protein product. Overexpression of this receptor in breast cancer is associated with increased disease recurrence and worse prognosis. HER2 appears to play roles in development cancer communication at the neuromuscular junction and regulation of cell growth and differentiation .
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